Article
The population genetics of the haemoglobinopathies.
Bailliere's clinical haematology - 1 Mar 1993
Flint J, Harding R M, Boyce A J, Clegg J B
Abstract excerpt
The haemoglobinopathies are the commonest single gene disorders known, and are so common in some regions of the world that the majority of the population carries at least one genetic abnormality affecting the structure or synthesis of the haemoglobin molecule. The prevalence of the common haemoglobinopathies (the alpha- and beta-thalassaemias, HbS, HbC and HbE) is almost certainly a result of the protection they...
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