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Hemoglobin variants shape the distribution of malaria parasites in human populations and their transmission potential

23 Oct 2017

Abstract excerpt

Hemoglobin variants C and S protect against severe malaria but their influence on parameters not directly linked to disease severity such as gametocyte carriage and infection chronicity is less well understood. To assess whether these infection-related phenotypes depend on the host hemoglobin genotype, we followed 500 Malian individuals over 1-2 years and determined their parasitological status during monthly...

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PMID: 29079846
DOI: 10.1038/s41598-017-14627-y

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