Article
META-ANALYSIS OF CONTINUOUS PHENOTYPES IDENTIFIES A GENE SIGNATURE THAT CORRELATES WITH COPD DISEASE STATUS.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2017
Scott Madeleine, Vallania Francesco, Khatri Purvesh
Abstract excerpt
The utility of multi-cohort two-class meta-analysis to identify robust differentially expressed gene signatures has been well established. However, many biomedical applications, such as gene signatures of disease progression, require one-class analysis. Here we describe an R package, MetaCorrelator, that can identify a reproducible transcriptional signature that is correlated with a continuous disease phenotype...
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