META-ANALYSIS OF CONTINUOUS PHENOTYPES IDENTIFIES A GENE SIGNATURE THAT CORRELATES WITH COPD DISEASE STATUS.

doi:10.1142/9789813207813_0026

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Article

META-ANALYSIS OF CONTINUOUS PHENOTYPES IDENTIFIES A GENE SIGNATURE THAT CORRELATES WITH COPD DISEASE STATUS.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2017

Scott Madeleine, Vallania Francesco, Khatri Purvesh

Abstract excerpt

The utility of multi-cohort two-class meta-analysis to identify robust differentially expressed gene signatures has been well established. However, many biomedical applications, such as gene signatures of disease progression, require one-class analysis. Here we describe an R package, MetaCorrelat...

Topics

Cohort Studies
Computational Biology
Databases, Genetic
Forced Expiratory Volume
Humans
Leukocytes, Mononuclear
Lung
Phenotype
Pulmonary Disease, Chronic Obstructive
Transcriptome

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