Article

Identifying Chronic Obstructive Pulmonary Disease from Integrative Omics and Clustering in Lung Tissue

2022-06-30

Abstract excerpt

<h4>Background: </h4> Chronic obstructive pulmonary disease (COPD) is a highly morbid and heterogenous disease. While COPD is defined by spirometry, many COPD characteristics are seen in cigarette smokers with normal spirometry. The extent to which COPD and COPD heterogeneity is captured in omics of lung tissue is not known. <h4>Methods: </h4> We clustered gene expression and methylation data in 78 lung tissue sam...

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Literature Corpus work: 3cb64acf-ce5b-5163-a9af-73c39600ca58
DOI: 10.21203/rs.3.rs-1712789/v1

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