Article
Induction of m2 polarization in primary culture liver macrophages from rats with acute pancreatitis.
PloS one - 1 Jan 2014
Xu Lixia, Yang Fen, Lin Rong, Han Chaoqun, Liu Jun, Ding Zhen
Abstract excerpt
BACKGROUND AND AIMS: Systemic inflammatory response syndrome (SIRS), a major process of severe acute pancreatitis (SAP), usually occurs after various activated proinflammatory cytokines, which are produced by macrophages such as liver macrophages. Macrophages can secrete not only proinflammatory mediators but also inhibitory inflammatory cytokines such as IL-10, leading to two different functional states defined...
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