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Article

Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer

28 Nov 2016

Abstract excerpt

The nuclear factor of activated T cells (NFAT) family proteins are transcription factors that regulate the expression of pro-inflammatory cytokines and other genes during the immune response. Although the NFAT proteins have been extensively investigated in the immune system, their role in cancer progression remains controversial. Here, we report that NFAT3 is highly expressed in various skin cancer cell lines and...

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PMID: 27893713
DOI: 10.1038/onc.2016.434

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