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Article

IKKβ-Mediated Resistance to Skin Cancer Development Is Ink4a/Arf-Dependent.

Molecular cancer research : MCR - 1 Sept 2017

Page Angustias, Bravo Ana, Suarez-Cabrera Cristian, Alameda Josefa P, Casanova M Llanos, Lorz Corina, Segrelles Carmen, Segovia José C, Paramio Jesús M, Navarro Manuel, Ramirez Angel

Abstract excerpt

IKKβ (encoded by IKBKB) is a protein kinase that regulates the activity of numerous proteins important in several signaling pathways, such as the NF-κB pathway. IKKβ exerts a protumorigenic role in several animal models of lung, hepatic, intestinal, and oral cancer. In addition, genomic and proteomic studies of human tumors also indicate that IKBKB gene is amplified or overexpressed in multiple tumor types. Here,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28584022
DOI: 10.1158/1541-7786.MCR-17-0157

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IKBKB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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