Article
Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditions.
Molecular cancer - 7 Apr 2006
Yin Weihong, Cheepala Satish, Roberts Jennifer N, Syson-Chan Keith, DiGiovanni John, Clifford John L
Abstract excerpt
BACKGROUND: Squamous cell carcinoma (SCC) of the skin is the most aggressive form of non-melanoma skin cancer (NMSC), and is the single most commonly diagnosed cancer in the U.S., with over one million new cases reported each year. Recent studies have revealed an oncogenic role of activated signal transducer and activator of transcription 3 (Stat3) in many human tumors, especially in those of epithelial origin,...
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