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Nuclear factor of activated T cells in cancer development and treatment

10 Mar 2015

Abstract excerpt

Since nuclear factor of activated T cells (NFAT) was first identified as a transcription factor in T cells, various NFAT isoforms have been discovered and investigated. Accumulating studies have suggested that NFATs are involved in many aspects of cancer, including carcinogenesis, cancer cell proliferation, metastasis, drug resistance and tumor microenvironment. Different NFAT isoforms have distinct functions in...

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PMID: 25766658
DOI: 10.1016/j.canlet.2015.03.005

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