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Article

Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis

3 Jul 2007

Abstract excerpt

Signal transducer and activator of transcription 3 (Stat3) is one of a family of cytoplasmic proteins that participate in normal cellular responses to cytokines and growth factors as transcription factors. Stat3 modulates various physiological functions including cell survival, cell-cycle regulation, and angiogenesis through regulation of gene expression, and its constitutive activation is associated with a...

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PMID: 17610223
DOI: 10.1002/mc.20342

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