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Article

The C-terminal extension of Mycobacterium tuberculosis Hsp16.3 regulates its oligomerization, subunit exchange dynamics and chaperone function.

The FEBS journal - 1 Jan 2017

Panda Alok Kumar, Chakraborty Ayon, Nandi Sandip Kumar, Kaushik Abhishek, Biswas Ashis

Abstract excerpt

Mycobacterium tuberculosis is a human pathogen that secretes a major immunodominant antigen, namely Hsp16.3, throughout the course of infection. Hsp16.3 belongs to the small heat shock protein family and exhibits a molecular chaperone function that is important for the growth and survival of M. tuberculosis in host cell macrophages. The importance of the N-terminal region for the structure and chaperone function...

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Identifiers

PMID: 27885799
DOI: 10.1111/febs.13975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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