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Article

Chaperone-like activity of Mycobacterium tuberculosis Hsp16.3 does not require its intact (native) structures.

Biochemistry. Biokhimiia - 1 Aug 2005

Chen Xiaoyou, Fu Xinmiao, Ma Yu, Chang Zengyi

Abstract excerpt

Small heat shock proteins (sHsps) were found to exhibit efficient chaperone-like activities under stress conditions although their native structures are severely disturbed. Here, using an alternative approach (site-directed mutagenesis), we obtained two structurally and functionally distinct Mycobacterium tuberculosis Hsp16.3 single-site mutant proteins. The G59W mutant protein (with Gly59 substituted by Trp) is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16212548
DOI: 10.1007/s10541-005-0202-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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