Article
The C-terminus of ClpC1 of Mycobacterium tuberculosis is crucial for its oligomerization and function.
PloS one - 1 Jan 2012
Bajaj Divya, Batra Janendra K
Abstract excerpt
Mycobacterium tuberculosis ClpC1 is a member of the Hsp100/Clp AAA+ family of ATPases. The primary sequence of ClpC1 contains two N-terminal domains and two nucleotide binding domains (NBD). The second NBD has a long C-terminal sub-domain containing several motifs important for substrate interaction. Generally, ClpC proteins are highly conserved, however presence of C-terminal domains of variable lengths is a...
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