Article
The association of small heat shock protein Hsp16.3 with the plasma membrane of Mycobacterium tuberculosis: dissociation of oligomers is a prerequisite.
Biochemical and biophysical research communications - 20 May 2005
Zhang Hui, Fu Xinmiao, Jiao Wangwang, Zhang Xuefeng, Liu Chong, Chang Zengyi
Abstract excerpt
Hsp16.3, a small heat shock protein from Mycobacterium tuberculosis (MTB), was originally identified as an immuno-dominant antigen and later found to be a major membrane protein. In vitro studies show that Hsp16.3 exists as nonamers and undergoes dynamic dissociation/re-association equilibrium in solutions. Nevertheless, neither the details nor the physiological implications of the presence of Hsp16.3 in the...
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