Article
Genome-wide minor histocompatibility matching as related to the risk of graft-versus-host disease.
Blood - 9 Feb 2017
Martin Paul J, Levine David M, Storer Barry E, Warren Edus H, Zheng Xiuwen, Nelson Sarah C, Smith Anajane G, Mortensen Bo K, Hansen John A
Abstract excerpt
The risk of acute graft-versus-host disease (GVHD) is higher after allogeneic hematopoietic cell transplantation (HCT) from unrelated donors as compared with related donors. This difference has been explained by increased recipient mismatching for major histocompatibility antigens or minor histocompatibility antigens. In the current study, we used genome-wide arrays to enumerate single nucleotide polymorphisms...
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