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Article

MHC Haplotype Matching for Unrelated Hematopoietic Cell Transplantation

26 Jan 2007

Abstract excerpt

BACKGROUND: Current criteria for the selection of unrelated donors for hematopoietic cell transplantation (HCT) include matching for the alleles of each human leukocyte antigen (HLA) locus within the major histocompatibility complex (MHC). Graft-versus-host disease (GVHD), however, remains a significant and potentially life-threatening complication even after HLA-identical unrelated HCT. The MHC harbors more than...

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Identifiers

PMID: 17378697
DOI: 10.1371/journal.pmed.0040008

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