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Targeting MUC15 Protein in Cancer: Molecular Mechanisms and Therapeutic Perspectives

1 Jun 2020

Abstract excerpt

MUC15, a member of the mucin family, is a heavily glycosylated transmembrane protein with the primary functions of lubricating surfaces, establishing a selective molecular barrier at the epithelium and mediating signal transduction. Aberrant expression of MUC15 plays a crucial role in the progression of multiple diseases, including malignant tumors. MUC15 has been identified as a tumor suppressor, but current...

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PMID: 32479243
DOI: 10.2174/1568009620666200601140639

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