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Article

Glycosylation of Tetraspanin CD151 Defines the Invasive Phenotype of Human Breast Cancer Cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 30 Nov 2025

Ohkawa Yuki, Yin Yuanqin, Nakano Miyako, Kanto Noriko, Ohno Shiho, Yamaguchi Yoshiki, Taniguchi Naoyuki

Abstract excerpt

CD151 belongs to the tetraspanin family and is a transmembrane glycoprotein that forms a complex with integrins. The complex is involved in cancer cell adhesion, growth, migration, and metastasis. Previous studies have shown that CD151 plays distinctly different roles in different types of cancer. Concerning this, we attempted to elucidate the roles that the N-glycosylation of CD151 plays in cell behavior. The...

Topics

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Breast Neoplasms
Cell Line, Tumor
Cell Movement
Glycosylation
Integrin beta1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Invasiveness

Source

Identifiers

PMID: 41217233
DOI: 10.1096/fj.202500093R

Genes

CD151
STT3B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Glycosylation of Tetraspanin CD151 Defines the Invasive Phenotype of Human Breast Cancer Cells.PMID 41217233Read ↗

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