Article
N-Glycosylation at Asn 402 Stabilizes N-Cadherin and Promotes Cell-Cell Adhesion of Glioma Cells.
Journal of cellular biochemistry - 1 Jun 2017
Xu Yaolin, Chang Ruiqi, Xu Fulin, Gao Yan, Yang Fuming, Wang Can, Xiao Jin, Su Zuopeng, Bi Yongyan, Wang Liying, Zha Xiliang
Abstract excerpt
Cadherin is crucial for cell-cell adhesion and N-glycosylation of N-cadherin has been implicated in the process of mammary, renal, and ovarian carcinogenesis. However, whether N-glycosylation of N-cadherin plays a role in glioma remains unknown. Previous studies had indicated that N-glycosylation could occur at three asparagine residues of N-cadherin. By generating and over-expressing N-glycosylation-deficient...
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