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Article

Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate.

Molecular biology of the cell - 1 Dec 2012

Tyler Ryan E, Pearce Margaret M P, Shaler Thomas A, Olzmann James A, Greenblatt Ethan J, Kopito Ron R

Abstract excerpt

Degradation of folding- or assembly-defective proteins by the endoplasmic reticulum-associated degradation (ERAD) ubiquitin ligase, Hrd1, is facilitated by a process that involves recognition of demannosylated N-glycans by the lectin OS-9/XTP3-B via the adaptor protein SEL1L. Most of our knowledg...

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Identifiers

PMID: 23097496
DOI: 10.1091/mbc.E12-06-0428
PMCID: PMC3521676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23097496-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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