Article
A genome-wide association study of essential hypertension in an Australian population using a DNA pooling approach.
Molecular genetics and genomics : MGG - 1 Apr 2017
Fowdar Javed Y, Grealy Rebecca, Lu Yi, Griffiths Lyn R
Abstract excerpt
Despite the success of genome-wide association studies (GWAS) in detecting genetic loci involved in complex traits, few susceptibility genes have been detected for essential hypertension (EH). We aimed to use pooled DNA GWAS approach to identify and validate novel genomic loci underlying EH susceptibility in an Australian case-control population. Blood samples and questionnaires detailing medical history, blood...
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