Article
Integrative genomic and transcriptomic analysis of hypertension in a Taiwanese population.
Journal of hypertension - 1 Oct 2026
Chang Sheng-Nan, Lee Guan-Wei, Chen Jien-Jiun, Wang Chih-Hsien, Chiu Fu-Chun, Huang Pang-Shuo, Chuang Eric Y, Tsai Chia-Ti
Abstract excerpt
OBJECTIVES: Hypertension is highly prevalent in Asian populations and represents a major cardiovascular risk factor. However, most genome-wide association studies (GWASs) and transcriptome-wide association studies (TWASs) have focused primarily on Caucasian cohorts. This study aimed to identify genetic loci and gene expression signatures associated with hypertension in an Asian population. METHODS: We analyzed 10...
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