Back to search

Article

Genomic Exploration of Essential Hypertension in African-Brazilian Quilombo Populations: A Comprehensive Approach with Pedigree Analysis and Family-Based Association Studies

2024-06-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Essential Hypertension (EH) is a global health issue. Despite extensive research, much of EH heritability remains unexplained. We investigated the genetic basis of EH in African-derived individuals from partially isolated quilombo populations in Vale do Ribeira (SP-Brazil). <h4>Methods</h4> Samples from 431 individuals (167 affected, 261 unaffected, 3 unknown) were genotyped u...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b62dfdb5-8fd1-5d04-8efb-356e72bb4e5a
DOI
10.1101/2024.06.26.24309531
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genomic Exploration of Essential Hypertension in African-Brazilian Quilombo Populations: A Comprehensive Approach with Pedigree Analysis and Family-Based Association StudiesDOI 10.1101/2024.06.26.24309531
Genomic Exploration of Essential Hypertension in African-Brazilian Quilombo Populations: A Comprehensive Approach With Pedigree Analysis and Family-Based Association Studies.Semantic proximity
Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.Semantic proximity
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.Semantic proximity
Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry.Semantic proximity
Association analyses of predicted loss-of-function variants prioritized 15 genes as blood pressure regulatorsSemantic proximity
An Academic Clinician's Road Map to Hypertension Genomics: Recent Advances and Future Directions MMXX.Semantic proximity
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.Semantic proximity
A genetic survey of patients with familial idiopathic intracranial hypertension residing in a Middle Eastern village: genetic association study.Semantic proximity
Meta-analysis and Multivariate GWAS Analyses in 77,850 Individuals of African Ancestry Identify Novel Variants Associated with Blood Pressure TraitsSemantic proximity
Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans.Semantic proximity
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.Semantic proximity
Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.Semantic proximity
Select a neighboring publication to make it the new centre.