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Article

All in the family? Analyzing the impact of family history in addition to genotype on medullary thyroid carcinoma aggressiveness in MEN2A patients.

Familial cancer - 1 Apr 2017

Long Kristin L, Etzel Carol, Rich Thereasa, Hyde Samuel, Perrier Nancy D, Graham Paul H, Lee Jeffrey E, Hu Mimi I, Cote Gilbert J, Gagel Robert, Grubbs Elizabeth G

Abstract excerpt

Several guidelines for patients with multiple endocrine neoplasia 2A (MEN2A) take into account genotype and family history of medullary thyroid carcinoma (MTC) disease aggressiveness. We sought to determine if an association exists independent of genotype, which could provide important information for counseling MEN2A patients in management of their MTC. Pedigrees of patients with ≥5 family members with MEN2A...

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Identifiers

PMID: 27864651
DOI: 10.1007/s10689-016-9948-7

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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