Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotype/phenotype correlations in multiple endocrine neoplasia type 2.

Endocrine-related cancer - 1 Dec 2024

Castinetti Frederic, Eng Charis

Abstract excerpt

Abstract: Multiple endocrine neoplasia type 2 (MEN 2) is a rare hereditary endocrine tumor syndrome caused by mutations in the rearranged during transfection (RET) gene. MEN 2 is divided into two main entities, MEN 2A and MEN 2B, both of which present with medullary thyroid cancer (MTC) in approximately 100% of cases and pheochromocytoma in 50% of cases. Specific RET mutations are associated with a risk of early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Gland Neoplasms
Share to Carcinoma, Neuroendocrine
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Multiple Endocrine Neoplasia Type 2a

Share to Pheochromocytoma

Share to Proto-Oncogene Proteins c-ret

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 39404342
DOI: 10.1530/ERC-24-0139

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotype/phenotype correlations in multiple endocrine neoplasia type 2.PMID 39404342Read ↗

Genotype-phenotype relationship in multiple endocrine neoplasia type 2. Implications for clinical management.Semantic proximity Read ↗

Multiple endocrine neoplasia type 2: 2007 update.Semantic proximity Read ↗

Multiple endocrine neoplasia type 2: evaluation of the genotype-phenotype relationship.Semantic proximity Read ↗

Multiple endocrine neoplasia type 2: A review.Semantic proximity Read ↗

Genetic and Clinical Features of Multiple Endocrine Neoplasia Types 1 and 2Semantic proximity Read ↗

Multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Hereditary Medullary Thyroid Cancer Genotype-Phenotype Correlation.Semantic proximity Read ↗

Multiple endocrine neoplasia: types 1 and 2.Semantic proximity Read ↗

[Genotype-phenotype correlations in multiple endocrine neoplasia type 2].Semantic proximity Read ↗

Multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Multiple endocrine neoplasia type 2 RET protooncogene database: repository of MEN2-associated RET sequence variation and reference for genotype/phenotype correlations.Semantic proximity Read ↗

Update on Multiple Endocrine Neoplasia Type 2: Focus on Medullary Thyroid CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.