Article

Mutation Spectrum and Associated Risks of Medullary Thyroid Cancer and All-Cause Mortality in Incidentally Identified MEN2A-Causing<i>RET</i>Variants

2024-11-23

Abstract excerpt

<h4>Importance</h4> RET pathogenic variants cause Multiple Endocrine Neoplasia type 2 (MEN2), characterised by medullary thyroid cancer (MTC). With increasing incidental identification of these variants in asymptomatic individuals outside family screening, their risk of MTC and all-cause mortality without intervention remain unknown in this context. <h4>Objective</h4> To determine the risk of MTC and all-cause mor...

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Literature Corpus work: fed76eb1-da5e-52f9-926b-fc92e8e66f00
DOI: 10.1101/2024.11.22.24317783

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