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Article

Systems analysis identifies miR-29b regulation of invasiveness in melanoma.

Molecular cancer - 16 Nov 2016

Andrews Miles C, Cursons Joseph, Hurley Daniel G, Anaka Matthew, Cebon Jonathan S, Behren Andreas, Crampin Edmund J

Abstract excerpt

BACKGROUND: In many cancers, microRNAs (miRs) contribute to metastatic progression by modulating phenotypic reprogramming processes such as epithelial-mesenchymal plasticity. This can be driven by miRs targeting multiple mRNA transcripts, inducing regulated changes across large sets of genes. The miR-target databases TargetScan and DIANA-microT predict putative relationships by examining sequence complementarity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27852308
DOI: 10.1186/s12943-016-0554-y
PMCID: PMC5112703

Genes

LAMC1
LASP1
PPIC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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