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Article

MicroRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis.

Pigment cell & melanoma research - 1 May 2015

Tembe Varsha, Schramm Sarah-Jane, Stark Mitchell S, Patrick Ellis, Jayaswal Vivek, Tang Yue Hang, Barbour Andrew, Hayward Nicholas K, Thompson John F, Scolyer Richard A, Yang Yee Hwa, Mann Graham J

Abstract excerpt

The role of microRNAs (miRNAs) in melanoma is unclear. We examined global miRNA expression profiles in fresh-frozen metastatic melanomas in relation to clinical outcome and BRAF mutation, with validation in independent cohorts of tumours and sera. We integrated miRNA and mRNA information from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25490969
DOI: 10.1111/pcmr.12343

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25490969-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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