Article
An integrative network-driven pipeline for systematic identification of lncRNA-associated regulatory network motifs in metastatic melanoma.
BMC bioinformatics - 23 Jul 2020
Singh Nivedita, Eberhardt Martin, Wolkenhauer Olaf, Vera Julio, Gupta Shailendra K
Abstract excerpt
BACKGROUND: Melanoma phenotype and the dynamics underlying its progression are determined by a complex interplay between different types of regulatory molecules. In particular, transcription factors (TFs), microRNAs (miRNAs), and long non-coding RNAs (lncRNAs) interact in layers that coalesce into large molecular interaction networks. Our goal here is to study molecules associated with the cross-talk between...
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