Back to search

Article

Post-transcriptional control of EMT is coordinated through combinatorial targeting by multiple microRNAs

2017-05-16

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is a process whereby cells undergo reversible phenotypic change, losing epithelial characteristics and acquiring mesenchymal attributes. While EMT underlies normal, physiological programs in embryonic tissue development and adult wound healing, it also contributes to cancer progression by facilitating metastasis and altering drug sensitivity. Using a cell model of EMT (human...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
25c08006-1301-5da2-99f6-dc879d9cfe5c
DOI
10.1101/138024
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Post-transcriptional control of EMT is coordinated through combinatorial targeting by multiple microRNAsDOI 10.1101/138024
Breast cancer lncRNA-microRNA categories: new targets for therapeutic interventionSemantic proximity
Identification of microRNA clusters cooperatively acting on Epithelial to Mesenchymal Transition in Triple Negative Breast CancerSemantic proximity
Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectivesSemantic proximity
Epithelial-mesenchymal transition transcription factors and miRNAs: “Plastic surgeons” of breast cancerSemantic proximity
Metastatic EMT Phenotype Is Governed by MicroRNA-200-Mediated Competing Endogenous RNA Networks.Semantic proximity
The Many-Faced Program of Epithelial–Mesenchymal Transition: A System Biology-Based ViewSemantic proximity
MicroRNA Regulation of Epithelial to Mesenchymal TransitionSemantic proximity
Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypesSemantic proximity
Unresolved Complexity in the Gene Regulatory Network Underlying EMTSemantic proximity
The Role of MicroRNA in the Regulation of Tumor Epithelial–Mesenchymal TransitionSemantic proximity
Combinatorial perturbation analysis reveals divergent regulations of mesenchymal genes during epithelial-to-mesenchymal transitionSemantic proximity
Combinatorial perturbation analysis reveals divergent regulations of mesenchymal genes during epithelial-to-mesenchymal transitionSemantic proximity
Select a neighboring publication to make it the new centre.