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Article

An Amino Acid in the Stalk Domain of N1 Neuraminidase Is Critical for Enzymatic Activity.

Journal of virology - 15 Jan 2017

Zanin Mark, Duan Susu, Wong Sook-San, Kumar Gyanendra, Baviskar Pradyumna, Collin Emily, Russell Charles, Barman Subrata, Hause Benjamin, Webby Richard

Abstract excerpt

Neuraminidase (NA) is a sialidase expressed on the surface of influenza A viruses that releases progeny viruses from the surface of infected cells and prevents viruses becoming trapped in mucus. It is a homotetramer, with each monomer consisting of a transmembrane region, a stalk, and a globular head with sialidase activity. We recently characterized two swine viruses of the pandemic H1N1 lineage,...

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Identifiers

PMID: 27847354
DOI: 10.1128/JVI.00868-16
PMCID: PMC5215329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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