Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Special Neuraminidase Stalk-Motif Responsible for Increased Virulence and Pathogenesis of H5N1 Influenza A Virus

16 Jul 2009

Abstract excerpt

The variation of highly pathogenic avian influenza H5N1 virus results in gradually increased virulence in poultry, and human cases continue to accumulate. The neuraminidase (NA) stalk region of influenza virus varies considerably and may associate with its virulence. The NA stalk region of all N1 subtype influenza A viruses can be divided into six different stalk-motifs, H5N1/2004-like (NA-wt), WSN-like,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Influenza Virus Research Studies
Share to Respiratory viral infections research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19609439
DOI: 10.1371/journal.pone.0006277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Special Neuraminidase Stalk-Motif Responsible for Increased Virulence and Pathogenesis of H5N1 Influenza A VirusPMID 19609439Read ↗

Neuraminidase stalk length and additional glycosylation of the hemagglutinin influence the virulence of influenza H5N1 viruses for mice.Semantic proximity Read ↗

The Neuraminidase Stalk Deletion Serves as Major Virulence Determinant of H5N1 Highly Pathogenic Avian Influenza Viruses in ChickenSemantic proximity Read ↗

Structure and Function of the NS1 Protein of Influenza A VirusSemantic proximity Read ↗

Pathogenicity and virulence of influenzaSemantic proximity Read ↗

A 20-Amino-Acid Deletion in the Neuraminidase Stalk and a Five-Amino-Acid Deletion in the NS1 Protein Both Contribute to the Pathogenicity of H5N1 Avian Influenza Viruses in Mallard DucksSemantic proximity Read ↗

Evolution and Adaptation of the Avian H7N9 Virus into the Human HostSemantic proximity Read ↗

H5N1 avian influenza virus without 80–84 amino acid deletion at the NS1 protein hijacks the innate immune system of dendritic cells for an enhanced mammalian pathogenicitySemantic proximity Read ↗

Species-Specific Contribution of the Four C-Terminal Amino Acids of Influenza A Virus NS1 Protein to VirulenceSemantic proximity Read ↗

Epidemiology and pathogenesis of influenzaSemantic proximity Read ↗

Identification of genome-wide nucleotide sites associated with mammalian virulence in influenza A virusesSemantic proximity Read ↗

Emergence and genetic variation of neuraminidase stalk deletions in avian influenza viruses.Semantic proximity Read ↗

Amino acid 316 of hemagglutinin and the neuraminidase stalk length influence virulence of H9N2 influenza virus in chickens and mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.