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Article

Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.

Journal of virology - 1 Dec 2012

Zhu Xueyong, McBride Ryan, Nycholat Corwin M, Yu Wenli, Paulson James C, Wilson Ian A

Abstract excerpt

Influenza virus neuraminidase (NA) cleaves off sialic acid from cellular receptors of hemagglutinin (HA) to enable progeny escape from infected cells. However, NA variants (D151G) of recent human H3N2 viruses have also been reported to bind receptors on red blood cells, but the nature of these receptors and the effect of the mutation on NA activity were not established. Here, we compare the functional and...

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Share to Influenza A Virus, H3N2 Subtype
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23015718
DOI: 10.1128/JVI.01426-12
PMCID: PMC3503043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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