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Article

HIV-1 Pr55Gag binds genomic and spliced RNAs with different affinity and stoichiometry.

RNA biology - 2 Jan 2017

Bernacchi Serena, Abd El-Wahab Ekram W, Dubois Noé, Hijnen Marcel, Smyth Redmond P, Mak Johnson, Marquet Roland, Paillart Jean-Christophe

Abstract excerpt

The HIV-1 Pr55Gag precursor specifically selects genomic RNA (gRNA) from a large variety of cellular and spliced viral RNAs (svRNAs), however the molecular mechanisms of this selective recognition remains poorly understood. To gain better understanding of this process, we analyzed the interactions between Pr55Gag and a large panel of viral RNA (vRNA) fragments encompassing the main packaging signal (Psi) and its...

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Identifiers

PMID: 27841704
DOI: 10.1080/15476286.2016.1256533
PMCID: PMC5270550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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