Article
The effect of polymorphisms in PD-1 gene on the risk of epithelial ovarian cancer and patients' outcomes.
Gynecologic oncology - 1 Jan 2017
Li Yan, Zhang Hui-Lan, Kang Shan, Zhou Rong-Miao, Wang Na
Abstract excerpt
OBJECTIVE: Programmed death-1 (PD-1), an important immunosuppressive molecule, plays a key role in tumor-cell-mediated immune escape. In the present study, we evaluated the effect of PD-1 gene polymorphisms on the risk of developing epithelial ovarian cancer (EOC) and patients' outcomes. METHODS: A case-control study was performed in 620 EOC patients and 620 control women. Survival data were available for 258...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
