Article
Programmed death-1 (PD-1) polymorphisms in Chinese patients with esophageal cancer.
Clinical biochemistry - 1 May 2014
Qiu Hao, Zheng Liang, Tang Weifeng, Yin Pengfei, Cheng Feng, Wang Lixin
Abstract excerpt
OBJECTIVES: Esophageal cancer is an extremely aggressive gastrointestinal malignancy, which appears to result from a complex interplay between genetic and environmental agents. The genetic loci conferring susceptibility have yet to be fully defined. Considering the role of programmed death-1 (PD-1) in immune regulation and tumor pathogenesis, we genotyped three functional single nucleotide polymorphisms (SNPs) in...
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