Article
Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates.
PloS one - 1 Jan 2016
Tsitoura Maria-Eleni I, Stavrou Eleana F, Maraziotis Ioannis A, Sarafidis Kosmas, Athanassiadou Aglaia, Dimitriou Gabriel
Abstract excerpt
BACKGROUND AND OBJECTIVES: Newborns delivered late-preterm (between 340/7 and 366/7 weeks of gestation) are at increased risk of respiratory distress syndrome (RDS). Polymorphisms within the surfactant protein (SP) A and B gene have been shown to predispose to RDS in preterm neonates. The aim of this study was to investigate whether specific SP-A and/or SP-B genetic variants are also associated with RDS in...
Topics
- Adrenal Cortex Hormones
- Alleles
- Birth Weight
- Cross-Sectional Studies
- Female
- Gene Expression
- Genetic Predisposition to Disease
- Gestational Age
- Haplotypes
- Heterozygote
- Humans
- Infant, Newborn
- Infant, Premature