Article
Surfactant proteins and genetic predisposition to respiratory distress syndrome.
Seminars in perinatology - 1 Dec 2002
Hallman Mikko, Haataja Ritva, Marttila Riitta
Abstract excerpt
Respiratory distress syndrome (RDS) is caused by surfactant deficiency at birth. The risk of RDS decreases from the gestational age of 24 weeks to full-term. Genetic and acquired factors additionally influence the risk of RDS. Surfactant deficiency in RDS is mainly caused by immaturity and a lack of differentiation of the alveolar epithelial cells involved in surfactant synthesis and secretion. A network of...
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