Article
Surfactant protein (SP) B associations and interactions with SP-A in white and black subjects with respiratory distress syndrome.
Pediatrics international : official journal of the Japan Pediatric Society - 1 Dec 2001
Floros J, Fan R, Diangelo S, Guo X, Wert J, Luo J
Abstract excerpt
BACKGROUND: The etiology of respiratory distress syndrome (RDS) is multifactorial and/or multigenic. Surfactant protein A (SP-A) and/or SP-B genetic variants have been identified as risk or protection factors for RDS. METHODS: We genotyped subjects with and without RDS for the SP-B intron 4 size variants (invariant (inv), deletion (del), insertion (ins) and for four (-18 (A/C), 1013 (A/C), 1580 (C/T), 9306 (A/G))...
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