Article
Polymorphisms of surfactant protein A genes and the risk of bronchopulmonary dysplasia in preterm infants.
The Turkish journal of pediatrics - 1 Jan 2000
Weber B, Borkhardt A, Stoll-Becker S, Reiss I, Gortner L
Abstract excerpt
The pathophysiology of bronchopulmonary dysplasia (BPD) as an inflammatory disorder secondary to neonatal respiratory distress syndrome (RDS) is not yet fully understood and still represents a major complication of prematurity. The main pathophysiologic feature of RDS is a primary surfactant deficiency in a structurally immature lung. Pulmonary surfactant contains 90 percent phospholipids and 10 percent proteins...
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