Article
Surfactant protein polymorphisms and neonatal lung disease.
Seminars in perinatology - 1 Dec 2006
Hallman Mikko, Haataja Ritva
Abstract excerpt
Here, we describe the approach of defining the genetic contribution to disease and discuss the polymorphisms of some genes that are associated with respiratory disease. The common allelic variants of SP-A1, SP-A2, SP-B, SP-C, and SP-D genes are associated with respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), or respiratory syncytial virus (RSV) bronchiolitis. The main SP-A haplotype,...
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