Article
Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.
Neonatology - 1 Jan 2013
Jo Heui Seung, Cho Sung-Il, Chang Yoon Hwan, Kim Beyong Il, Choi Jung-Hwan
Abstract excerpt
BACKGROUND: Insufficiency of the pulmonary surfactant system is the primary cause of respiratory distress syndrome (RDS) in preterm infants. Genetic factors, including specific single-nucleotide polymorphisms in the genetic components of surfactant protein A (SP-A1 and SP-A2), affect protein structure and function, as well as risk of RDS. OBJECTIVE: We investigated the association between variations in SP-A...
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