Article
Association of tumor necrosis factor α -308G/A and interleukin-6 -174G/C gene polymorphism with pneumonia-induced sepsis.
Journal of critical care - 1 Oct 2015
Feng Bo, Mao Zheng-rong, Pang Kai, Zhang Shao-lei, Li Li
Abstract excerpt
PURPOSE: Sepsis is a lethal outcome of the inflammation and coagulation process. Human interleukin (IL)-6 and tumor necrosis factor (TNF) α are well-known inflammation factors closely associated with sepsis. In the present study, we aim to investigate the association of promoter-region polymorphi...
Topics
- Adolescent
- Adult
- Aged
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Intensive Care Units
- Interleukin-6
- Male
- Middle Aged
- Odds Ratio
- Pneumonia
- Polymorphism, Single Nucleotide
- Shock, Septic
- Tumor Necrosis Factor-alpha