Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytokine-related genotypic differences in peak interleukin-6 blood levels of patients with SIRS and septic complications.

The Journal of trauma - 1 Nov 2005

Watanabe Eizo, Hirasawa Hiroyuki, Oda Shigeto, Shiga Hidetoshi, Matsuda Kenichi, Nakamura Masataka, Abe Ryuzo, Nakada Takaaki

Abstract excerpt

BACKGROUND: The aim of the present study was to investigate whether tumor necrosis factor (TNF), interleukin (IL)-1, and IL-6-related genotypic differences affect IL-6 blood levels in patients with systemic inflammatory response syndrome (SIRS) in an intensive care unit (ICU). METHODS: Seven polymorphisms of TNF, IL-1, and IL-6-related polymorphisms were studied with an allele-specific polymerase chain reaction....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Critical Illness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1

Share to Interleukin-6

Share to Linkage Disequilibrium

Share to Shock, Septic

Share to Systemic Inflammatory Response Syndrome

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 16385298
DOI: 10.1097/00005373-200511000-00025

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytokine-related genotypic differences in peak interleukin-6 blood levels of patients with SIRS and septic complications.PMID 16385298Read ↗

Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor- and interleukin-1-related gene polymorphisms.Semantic proximity Read ↗

Genomic polymorphism within interleukin-1 family cytokines influences the outcome of septic patients.Semantic proximity Read ↗

[Genomic polymorphism within interleukin-1 family cytokines influences the outcome of septic patients].Semantic proximity Read ↗

Effect of the interleukin-6 promoter polymorphism (−174 G/C) on the incidence and outcome of sepsisSemantic proximity Read ↗

Association between Interleukin-6 Promoter Polymorphism (-174 G/C), Serum Interleukin-6 Levels and Mortality in Severe Septic Patients.Semantic proximity Read ↗

The association of interleukin 6 haplotype clades with mortality in critically ill adults.Semantic proximity Read ↗

Clinical associations of host genetic variations in the genes of cytokines in critically ill patients.Semantic proximity Read ↗

Clinical relevance of single nucleotide polymorphisms within the 13 cytokine genes in North Indian trauma hemorrhagic shock patients.Semantic proximity Read ↗

The interleukin-6 (IL6)-174 G/C promoter genotype is associated with the presence of septic shock and the ex vivo secretion of IL6.Semantic proximity Read ↗

Association between IL-6 polymorphisms and sepsisSemantic proximity Read ↗

Association between lymphotoxin-alpha (tumor necrosis factor-beta) intron polymorphism and predisposition to severe sepsis is modified by gender and age.Semantic proximity Read ↗

Mortality in adult intensive care patients with severe systemic inflammatory response syndromes is strongly associated with the hypo-immune TNF -238A polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.