Article
Sorting receptor SORLA: cellular mechanisms and implications for disease.
Cellular and molecular life sciences : CMLS - 1 Apr 2017
Schmidt Vanessa, Subkhangulova Aygul, Willnow Thomas E
Abstract excerpt
Sorting-related receptor with A-type repeats (SORLA) is an intracellular sorting receptor that directs cargo proteins, such as kinases, phosphatases, and signaling receptors, to their correct location within the cell. The activity of SORLA assures proper function of cells and tissues, and receptor dysfunction is the underlying cause of common human malignancies, including Alzheimer's disease, atherosclerosis, and...
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