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Article

Regulatory Roles of Sortilin and SorLA in Immune-Related Processes

7 Jan 2019

Abstract excerpt

Sortilin, also known as Neurotensin Receptor-3, and the sorting-related receptor with type-A repeats (SorLA) are both members of the Vps10p domain receptor family. Initially identified in CNS cells, they are expressed in various other cell types where they exert multiple functions. Although mostly studied for its involvement in Alzheimer's disease, SorLA has recently been shown to be implicated in immune response...

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PMID: 30666202
DOI: 10.3389/fphar.2018.01507

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