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Article

Personalized vaccines for cancer immunotherapy.

Science (New York, N.Y.) - 23 Mar 2018

Sahin Ugur, Türeci Özlem

Abstract excerpt

Cancer is characterized by an accumulation of genetic alterations. Somatic mutations can generate cancer-specific neoepitopes that are recognized by autologous T cells as foreign and constitute ideal cancer vaccine targets. Every tumor has its own unique composition of mutations, with only a small fraction shared between patients. Technological advances in genomics, data science, and cancer immunotherapy now...

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Source

Identifiers

PMID: 29567706
DOI: 10.1126/science.aar7112

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