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Article

Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus.

Genes and immunity - 1 Dec 2016

Gabrielsen I S M, Viken M K, Amundsen S S, Helgeland H, Holm K, Flåm S T, Lie B A

Abstract excerpt

Genetic polymorphisms in the endoplasmic reticulum aminopeptidase (ERAP)1 and ERAP2 genes have been associated with several autoimmune diseases (AIDs) at a genome-wide significance level. In this study, we performed a cis expression quantitative trait locus (eQTL) screen to investigate whether seven fine-mapped AID single-nucleotide polymorphisms (SNPs) in the ERAP-region influence the gene-expression levels of...

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Share to Aminopeptidases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Minor Histocompatibility Antigens

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Source

Identifiers

PMID: 27829666
DOI: 10.1038/gene.2016.39

Genes

ERAP2
ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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