Article
Assessing interactions between Ghsr and Mc3r reveals a role for AgRP in the expression of food anticipatory activity in male mice.
Endocrinology - 1 Dec 2014
Girardet Clemence, Mavrikaki Maria, Southern Mark R, Smith Roy G, Butler Andrew A
Abstract excerpt
The stomach hormone ghrelin and hypothalamic melanocortin neurons belong to a gut-brain circuit controlling appetite and metabolic homeostasis. Mice lacking melanocortin-3 receptor (Mc3rKO) or growth hormone secretagogue receptor (GhsrKO) genes exhibit attenuated food anticipatory activity (FAA),...
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