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Article

The ADH1B and DRD2 gene polymorphism may modify the protective effect of the ALDH2 gene against heroin dependence.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2013

Wang Tzu-Yun, Lee Sheng-Yu, Chen Shiou-Lan, Chang Yun-Hsuan, Chen Shih-Heng, Chu Chun-Hsien, Huang San-Yuan, Tzeng Nian-Sheng, Wang Chen-Lin, Yeh Pin-Hsi, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

Understanding the influences of genes involved in dopamine and serotonin metabolism, such as the aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) genes, is critical for understanding addictive behavior. In addition, dopamine D2 receptor (DRD2) gene may also interact with the dopamine metabolizing genes and link to addiction. Therefore, we investigated the association between the ALDH2, ADH1B...

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Share to Alcohol Dehydrogenase
Share to Aldehyde Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Data Interpretation, Statistical

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Share to Receptors, Dopamine D2

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Source

Identifiers

PMID: 23266708
DOI: 10.1016/j.pnpbp.2012.12.011

Genes

ALDH2
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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